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Search Results - sha+jin
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Immune-Activated Genome-Edited Cancer Vaccines for Next-Generation Immunotherapy
This technology introduces a genome-edited whole-cell cancer vaccine engineered to remove key immune evasion signals such as CD47, enabling robust macrophage activation and enhanced antigen presentation. The edited, non-replicating tumor cells stimulate durable, systemic anti-tumor immunity with fewer off-target effects than antibody-based checkpoint...
Published: 11/21/2025
|
Inventor(s):
Kaiming Ye
,
Sha Jin
,
Subhadra Jayaraman Rukmini
Keywords(s):
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Campus > Binghamton University
Decellularized Matrix Technology for Functional, Vascularized Pancreatic Islet Organoids
This invention uses a detergent-free decellularized pancreatic extracellular matrix (dpECM) to direct human pluripotent stem cells into self-assembled, vascularized pancreatic islet organoids. By recreating the native pancreatic microenvironment, the technology promotes β-cell maturation, multicellular organization, and glucose-responsive insulin...
Published: 11/26/2025
|
Inventor(s):
Sha Jin
,
Kaiming Ye
,
Huanjing Bi
Keywords(s):
#SUNYresearch
,
Technologies
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Campus > Binghamton University