Search Results - ryan+stowe

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Anticancer Compounds That Selectively Target and Destroy Cancer-Related Proteins
Demonstrates In Vivo Safety and Efficacy in Breast Cancer Models This set of anticancer compounds selectively degrades or inhibits cancer-related histone deacetylase proteins. These proteins are commonly overexpressed in various cancer types, and class I histone deacetylase proteins activate oncogenes that cause tumor formation, cancer progression,...
Published: 12/1/2021   |   Inventor(s): Daiqing Liao, Xuan Zhang, Yufeng Xiao, William Roush, Ryan Stowe, Guangrong Zheng
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Benzoylhydrazide HDAC Inhibitors with Low Toxicity for Treating Cancer
Compounds Display Potent Inhibition of Cancer-Causing Enzymes and Suppression of Solid Tumor Growth This class of small-molecule HDAC inhibitors has a novel benzoylhydrazide scaffold with potential to treat cancer, neurodegenerative disorders, and metabolic diseases. Cancer is the second leading cause of death in the United States, with more than 1.5...
Published: 6/27/2021   |   Inventor(s): Daiqing Liao, William Roush, Ryan Stowe
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics