Search Results - rex+moore

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Bifunctional fusion protein for biofilm degradation and quorum sensing disruption
Background Bacterial biofilms pose a major challenge in clinical and industrial environments due to their dense extracellular matrix and heightened tolerance to antibiotics and immune responses. Infections involving biofilms, particularly those caused by Pseudomonas aeruginosa, are difficult to eradicate and contribute to chronic wounds, persistent...
Published: 1/30/2026   |   Inventor(s): Hugh Smyth, Tom Smisek, Rex Moore, Nila Murali, John Schroeder, Walter Fast
Keywords(s):  
Category(s): Life sciences > Therapeutics > Biologic
Inhalable vancomycin–DNase powder for eradication of MRSA lung infections
Background Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of hospital-acquired pneumonia, contributing to elevated mortality, prolonged hospitalizations, and increased healthcare costs. The persistence of MRSA in the lungs is largely due to its ability to form biofilms and generate persister cells, both of which protect the bacteria...
Published: 1/13/2026   |   Inventor(s): Hugh Smyth, Rex Moore
Keywords(s):  
Category(s): Life sciences > Therapeutics > Formulation