Search Results - prevents

2 Results Sort By:
mTOR Inhibition for the Prevention of Epithelial Stem Cell Loss and Mucositis
The integrity of the epidermis and mucosal epithelia is highly dependent on self-renewing stem cells and, therefore, is vulnerable to physical and chemical damage from common cancer treatments, such as radiation or chemotherapy. Consequently, many cancer patients undergoing these treatments develop mucositis, a debilitating condition involving painful...
Published: 12/26/2024   |   Inventor(s): Ramiro Iglesias-Bartolome, Vyomesh Patel, Ana Cotrim, Alfredo Molinolo, James Mitchell, J Silvio Gutkind
Keywords(s): CBXXXX, Cell, CXXXXX, Epithelial, inhibition, mTOR, Mucositis, PREVENTS, PROTECTS, Radiation-induced, Senescence, Stem
Category(s): Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing
Prevention and Treatment of Multiple Sclerosis (MS) by Administering E-Selectin
The invention is a method and composition for inhibiting or treating symptoms of inflammatory demyelination or inflammation associated with autoimmune disorders. This is accomplished by administering recombinant E-selectin protein intranasally and resulting in E selectin-specific regulatory T-cells. These regulatory T-cells suppress activation of blood...
Published: 4/8/2024   |   Inventor(s): Jacqueline Shukaliak-Quandt
Keywords(s): ANIMAL, Autoimmune, BBXXXX, BCXXXX, brain, Damage, EAE, Encephalomylelitis, e-selectin, EXPERIMENTAL, IMMUNOLOGICAL, Model, Multiple sclerosis, NB1HXX, NB1JXX, NB1XXX, NBXXXX, NXXXXX, PREVENTS, Tolerization
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Neurology