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Search Results - nisha+narayan
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SIRT2 Inhibitors as Novel Therapeutics for Myocardial Infarction and Ischemic Stroke and to Prevent Necrosis
Sirtuin 2 (SIRT2) inhibitors to reduce necrosis and, thereby, as novel therapeutics to treat ischemic stroke and myocardial infarction. Accumulating evidence indicates that programmed necrosis plays a critical role in cell death during ischemia-reperfusion. NIH investigators have shown that the NAD-dependent deacetylase SIRT2 binds constitutively...
Published: 4/8/2024
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Inventor(s):
Toren Finkel
,
Nisha Narayan
Keywords(s):
Against
,
AGK2
,
deacetylase
,
IB1FXX
,
IB1XXX
,
IBXXXX
,
inhibitor
,
IXXXXX
,
NAD-dependent
,
NB1HXX
,
NB1XXX
,
NBXXXX
,
NECROSIS
,
NXXXXX
,
PROTECTS
,
Sirt2
Category(s):
Collaboration Sought > Collaboration
,
Application > Diagnostics
,
Application > Research Materials
,
Application > Therapeutics
,
TherapeuticArea > Cardiology
,
TherapeuticArea > Neurology