Search Results - ngf%2fexendin-4

1 Results Sort By:
Adeno-Associated Virus Gene Therapy for Diabetes and Obesity
This invention is directed to adeno-associated virus (AAV) vector delivery of exendin-4 (Ex-4) to salivary glands as treatment for diabetes and obesity. Ex-4 is a potent and long-acting agonist of the receptor for glucagon-like peptide 1 (GLP-1). Scientists at NIDCR have shown that AAV-mediated delivery of Ex-4 resulted in improved glucose homeostasis...
Published: 12/26/2024   |   Inventor(s): Giovanni Di Pasquale, Edward Mannucci, John (Jay) Chiorini
Keywords(s): DIABETES, EPITHELIA, Expression, Fusion, GBXXXX, Gland, IBXXXX, Listed LPM Contreras as of 4/15/2015, NGF/exendin-4, Novel, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Protein, Salivary, treatment
Category(s): Application > Therapeutics