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An engineered methyltransferase enzyme for improved production of benzylisoquinoline alkaloids
Background Tetrahydropapaverine (THP) and papaverine are naturally occurring plant alkaloids that are commercially important. THP is a precursor of the drugs atracurium and cisatracurium, used as muscle relaxants. Papaverine is used as an antispasmodic. These clinically useful molecules may be synthesized using traditional organic synthesis methods...
Published: 11/27/2023   |   Inventor(s): Andrew Ellington, Simon d’Oelsnitz, Mohammad Javanmardi, Ross Thyer
Keywords(s):  
Category(s): Life sciences > Research tools > Reagent, Life sciences > Diagnostic