Search Results - michele+marcolongo

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Biomimetic aggrecan injection for lower back pain treatment
PAGE TITLE Overview PAGE SUMMARY Proteoglycans (PGs) are a major building block and a hydrating agent in the extracellular matrix, which maintains structural organization of cells within tissues. PGs retain water and regulate flow of minerals and other nutrients, lubricate and provide mechanical support to the tissues. The combination of PGs and...
Published: 7/16/2024   |   Inventor(s): Michele Marcolongo, Caroline Schauer, Sumona Sarkar, Edward Vresilovic, Benjamin Jackson
Keywords(s): Aggrecan, Biomaterial, Biomimetic, Degenerative disc disease, Injectable, Lower back pain, Minimally Invasive, Spine
Category(s): Life Sciences, Medical Devices & Diagnostics
Associating Hydrogels for nucleus pulposus Replacement in intervertebral discs
PAGE TITLEOverview PAGE SUMMARY A prosthetic nucleus prepared from blends of polyvinylalcohol and polyvinyl pyrollidone or its copolymers for replacement of the nucleus pulposus in intervertebral discs is provided. Also provided are methods of replacing the nucleus pulposus and treating disc degeneration-associated pain in mammals using this prosthetic...
Published: 5/19/2022   |   Inventor(s): Michele Marcolongo, Anthony Lowman
Keywords(s):  
Category(s): Materials & Chemicals, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Implantable/Prosthetic Devices