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pH-responsive hydrogel technology for enhanced oral delivery of therapeutic proteins
Improved hydrogel copolymers, made from itaconic acid and N-vinyl­pyrrolidone, enable oral delivery of therapeutic proteins by protecting them in the stomach and releasing them in the intestine. This enhances protein bioavailability and pharmacokinetics. Background Oral delivery of therapeutic proteins presents significant challenges due to the...
Published: 10/3/2024   |   Inventor(s): Nicholas Peppas, Michael Koetting
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Synthetic biology