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Search Results - mei+chai+zheng
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Exosome Gene Therapy for Treating Inner Ear Disease
Extracellular Vesicles Directly Target Inner Ear Cells to Correct Malfunctioning Genes In Vivo This in vivo gene therapy strategy combines selective gene editors with the cell targeting capability using extracellular vesicles for safe and targeted delivery., Hearing loss affects at least 1 in 500 newborns, and over 50% are hereditary in nature. One...
Published: 9/3/2024
|
Inventor(s):
Mei He
,
Xiaoshu Pan
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Gene Therapy
,
Technology Classifications > Human Health Care > Drug Delivery
Droplet-Based Electroporation for High-Throughput Biomolecular Cargo Loading of Extracellular Vesicles and Exosomes
Optimizes Cargo Loading a Sub-Cellular Scale, Enabling the Scaling of Drug Manufacturing This electroporation platform enables the efficient, large-scale loading of biomolecular cargo into extracellular vesicles (EVs) and exosomes. Extracellular vesicles (EVs) are biocompatible, have fast cellular uptake, and can penetrate biological barriers, making...
Published: 4/1/2024
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Inventor(s):
Mei He
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
,
Technology Classifications > Human Health Care > Drug Delivery
Genomics-based Diagnostic Assay for Cancer
Abstract: Molecular profiling with high throughput assays has gained utility in the management of select cancer patients and several gene expression-based assays are now marketed for improved prognostic accuracy for patients with cancer. This technology describes a genomics based diagnostic assay for the diagnosis and prognosis of cancer patients. ...
Published: 4/8/2024
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Inventor(s):
Steven Libutti
,
Mei He
Keywords(s):
assay
,
CANCER
,
diagnostic
,
Genomics
,
PROGNOSIS
Category(s):
Application > Diagnostics
,
TherapeuticArea > Oncology
,
Collaboration Sought > Licensing
Efficient and Scalable Cellular Production of Immune Functional Extracellular Vesicles
Utilizes Low-Power, Near-UV Light Induction to Produce Dendritic Cell-Derived Extracellular Vesicles for Use in Immunotherapy This simple, straightforward, and scalable production of dendritic cell-derived extracellular vesicles (DC-EVs) employs low-power, near-UV light. Dendritic cells are the most potent antigen-presenting cells and the key initiator...
Published: 7/24/2023
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Inventor(s):
Mei He
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Drug Delivery
High Peak Power (≥ 10 mW) Quantum Cascade Superluminescent Emitter
Princeton Docket # 15-3101-1Researchers in the Department of Electrical Engineering at Princeton University have developed a novel Quantum Cascade (QC) device to emit mid-infrared (mid-IR) superluminescent light with high power output. The high power superluminescent light has applications in mid-IR broadband absorption spectroscopy and mid-IR optical...
Published: 3/30/2022
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Inventor(s):
Nyan Aung
,
Mei Chai Zheng
,
Claire Gmachl
Keywords(s):
laser
Category(s):
Mechanical/Electrical Engineering