Search Results - masayuki+noguchi

3 Results Sort By:
Bile Acids and Other Agents that Modulate the Gut Microbiome for the Treatment of Liver Cancer
Abstract: Primary liver tumors and secondary hepatic malignancies are among the leading causes of cancer-related deaths. Liver metastases account for 95% of all hepatic cancers, and the liver is the most common site for organ metastasis in the body. The gut microbiome serves an important role in antitumor immunity regulating the efficacy of chemo- and...
Published: 4/8/2024   |   Inventor(s): Tim Greten, Chi Ma
Keywords(s): Bile Acid, Greten, Liver cancer, Natural Killer T Cells, NKT cells
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing
Methods for Diagnoses and Treatment of XSCID
The invention provides a method of diagnosing X-linked severe combined immunodeficiency (XSCID) in males or determining whether females are carriers. This method is based upon the presence of either a mutated or truncated IL-2Rgamma gene. The invention also discloses a method of treating XSCID as well as a method for monitoring the therapy. Lastly,...
Published: 7/25/2024   |   Inventor(s): Warren Leonard, Masayuki Noguchi, Wesley Mcbride
Keywords(s): Hyper IgM syndrome, IA3XXX, IAXXXX, IB3XXX, IBXXXX, ICXXXX, Immunodeficiency 2, Immunodeficiency 4, Immunodeficiency-3, IXXXXX, Severe combined immunodeficiency, Severe combined immunodeficiency, x-linked, Wiskott Aldrich syndrome
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics, TherapeuticArea > Immunology
Production of cyclopeptibodies with high target affinity and specificity that can be used as a replacement for antibodies
Background Antibodies find widespread use as therapeutic agents and for diagnostic, imaging, and immunodetection applications. Major limitations of antibodies, however, are their complex structure, limited stability, poor tissue penetration, complex manufacturing process, and associated high costs of production. Despite their numerous and important...
Published: 5/7/2024   |   Inventor(s): Rudi Fasan, Yu Gu
Keywords(s):  
Category(s): Therapeutic