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Engineered Protein with Enhance Antibody Targeting and Cytotoxic Response Properties
Problem: Antibody-based therapies have demonstrated promising results. Following binding of the mAb to its tumor target, interactions of the Fc-portion with Fc-receptors (Fc-R) expressed by effector cells (e.g. natural killer (NK) cells, macrophages and T-cells) may result in complement-dependent cytotoxicity (CDC) and antibody-dependent cellular cytotoxicity...
Published: 7/16/2026   |   Updated: 7/16/2026   |   Inventor(s): Mark Greene, Hongtao Zhang, Xiaomin Song, Zhaocai Zhou, Ramachandran Murali, Masahide Tone, Zhiqiang Zhu, Lian Lam, Zheng Cai
Keywords(s): Bioengineering
Category(s): Technology Classifications > Therapeutics