Search Results - marian+hettiaratchi

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Moderate-Affinity Affibodies for Controlled Protein Delivery and Bioactivity
1. Technology Overview The invention introduces a novel method for controlled protein delivery and bioactivity using moderate-affinity affibodies. These 58-amino acid peptides can specifically bind to various proteins, allowing for the controlled release or sequestration of multiple payloads within a single vehicle. The technology leverages the conjugation...
Published: 1/8/2026   |   Inventor(s): Marian Hettiaratchi, Henry Hochstatter, Veronica Spaulding, Jonathan Dorogin, Alycia Galindo, Chandler Asnes, Madeline Martin, Justin Svendsen
Keywords(s):  
Category(s): Medical Devices, Therapeutics, Materials Science
Bile Acids and Other Agents that Modulate the Gut Microbiome for the Treatment of Liver Cancer
Abstract: Primary liver tumors and secondary hepatic malignancies are among the leading causes of cancer-related deaths. Liver metastases account for 95% of all hepatic cancers, and the liver is the most common site for organ metastasis in the body. The gut microbiome serves an important role in antitumor immunity regulating the efficacy of chemo- and...
Published: 4/22/2025   |   Inventor(s): Tim Greten, Chi Ma
Keywords(s): Bile Acid, Greten, Liver cancer, Natural Killer T Cells, NKT cells
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing