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Targeted modulation of noncoding BMPR2 sequences increases protein expression for treatment of pulmonary arterial hypertension
Problem: Pulmonary arterial hypertension (PAH) is a severe lung disease characterized by elevated pulmonary arterial pressure that is estimated to affect 5,000-15,000 people in the US. Without proper treatment, the elevated pressure leads to heart failure and eventually death—median survival without treatment is around 2-3 years. Management and...
Published: 6/20/2024   |   Inventor(s): Yoseph Barash, Nicholas Hand, Louis Ghanem, David Lee
Keywords(s): Pulmonary
Category(s): Technology Classifications > Therapeutics