Search Results - kyle+aleshire

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NOVEL PHOSPHORYLATION REAGENT TO PRODUCE BIOLOGICALLY ACTIVE COMPOUNDS
An invention to utilize “green chemistry” in a metal-free, mild condition to synthesize pharmaceutical agents. The Invention This invention is a powerful phosphorylation reagent called NHP-thiourea that can generate a phosphorus-carbon (P-C) bond and phosphorus-nitrogen (P-N) bond with metal-free reaction conditions. These P-C and P-N...
Published: 8/16/2022   |   Inventor(s): Kyle Aleshire, Jun Yong Kang, Karimulla Mulla
Keywords(s): Chemistry, Life Science - Biotech
Category(s): Chemistry, All, Therapeutics, Pharmaceuticals, Drug Delivery
Decrease Toxic Metal Residues in Medicine (N-Heterocyclic Phosphines)
Invention SummaryThe invention is a new synthetic method for generation of P-C bonds (phosphorus-carbon bonds) with transition-metal-free reaction conditions. Phosphorus carbon bonds are often found in pharmaceuticals and antimicrobial natural products. Accordingly, creation of P-C bonds under metal-free reaction conditions would be highly desirable...
Published: 6/11/2015   |   Inventor(s): Kyle Aleshire, Jun Yong Kang, Karimulla Mulla
Keywords(s): Biotech, Chemistry
Category(s): Chemistry, All, Therapeutics, Pharmaceuticals, Drug Delivery