Search Results - kelton+schleyer

2 Results Sort By:
Ultrasensitive Fluorogenic Probe to Detect Heparanase Activity
Single-Step Fluorescence Assay Facilitates High-Throughput Screening of Heparanase Inhibitors This fluorogenic probe tests for the presence of heparanase and facilitates rapid screening for heparanase inhibitors to aid the development of cancer therapeutics. Heparanase is an enzyme overexpressed in many carcinomas, sarcomas, hematological malignancies,...
Published: 11/19/2021   |   Inventor(s): Lina Cui, Jun Liu, Kelton Schleyer
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Fluorogenic Probe for More Precise Detection of Cathepsin L Activity
Demonstrates Good Selectivity and High Sensitivity for the Protease Within 10 Minutes This fluorogenic probe rapidly detects cathepsin L activity with high sensitivity and selectivity. Cathepsin L is a lysosomal protease upregulated in many diseases and forms of cancer. Proteases are involved in the development and progression of cancer; inhibiting...
Published: 8/25/2021   |   Inventor(s): Lina Cui, Kelton Schleyer
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Human Health Care > Diagnostics