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A method for measuring and modeling quantitative sequence-function relationships for possible applications in transcriptional misregulation, antibody optimization, and antigenic epitope development

Princeton University Invention # 10-2580 Researchers in the Physics and Molecular Biology Departments, Princeton University, have developed a method that uses a simple mutational assay and information theory to decipher the molecular mechanisms by which a biological sequence functions, either in vitro or in living cells. This technology was demonstrated...

Published: 3/30/2022 | Inventor(s): Justin b. Kinney, Edward Cox, Curtis Callan, Anand Murugan

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Category(s): Biotechnology/Pharmaceuticals