Search Results - jovanka+voyich

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Targeting Poly-Gamma-Glutamic Acid to Treat Staphylococcus Epidermidis and Related Infections

Over the past decade, Staphylococcus epidermidis has become the most prevalent pathogen involved in nosocomial infections. Usually an innocuous commensal microorganism on human skin, this member of the coagulase-negative group of staphylococci can cause severe infection after penetration of the epidermal protective barriers of the human body. In the...

Published: 7/25/2024 | Inventor(s): Yufeng Yao, Jovanka Voyich, Cuong Vuong, Stanislava Kocianova, Frank DeLeo, Michael Otto

Keywords(s): Capsule, DA3XXX, DAXXXX, DC4XXX, DCXXXX, DDXXXX, DXXXXX, Edidermis, Poly-gamma-DL-glutamate, Staphylococcus

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Vaccines, TherapeuticArea > Infectious Disease

Synthetic Procedure and Cancer Treatment Using Cisplatin Derivatives

Cisplatin analogs for treating cancers The Invention Platinum-based drugs, such as Cisplatin, are commonly prescribed drugs for cancer treatment. However, these drugs are limited by a narrow spectrum of activity, treatment resistance, and can include toxic side effects. This invention introduces a series of novel compounds and methods of treatment...

Published: 4/9/2024 | Inventor(s): Bryan Spangelo, Haesook Han, Pradip Bhowmik, Pear (Ontida) Tanthmanatham, Van Vo

Keywords(s):

Category(s): Chemistry, All

Synthetic Procedure and Cancer Treatment Using Cisplatin Derivatives

Invention SummaryA series of cisplatin derivatives were synthesized and characterized, superseding cisplatin, carboplatin, and oxaliplatin—compounds used for the clinical treatment of various cancers. The synthetic process for the manufacture of these compounds and their analogues are provided. The antitumor activities of these compounds were...

Published: 6/4/2015 | Inventor(s): Pradip Bhowmik, Haesook Han, Bryan Spangelo, Pear (ontida) Tanthmanatham, Van Vo

Keywords(s):

Category(s): Chemistry, All