Search Results - bryan+spangelo

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Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth

An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...

Published: 9/15/2025 | Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij

Keywords(s): Driving Lifelong Health

Category(s): Life Science, Medical Devices, Imaging, Acoustics, Women's Health

Synthetic Procedure and Cancer Treatment Using Cisplatin Derivatives

Cisplatin analogs for treating cancers The Invention Platinum-based drugs, such as Cisplatin, are commonly prescribed drugs for cancer treatment. However, these drugs are limited by a narrow spectrum of activity, treatment resistance, and can include toxic side effects. This invention introduces a series of novel compounds and methods of treatment...

Published: 1/13/2025 | Inventor(s): Bryan Spangelo, Haesook Han, Pradip Bhowmik, Pear (Ontida) Tanthmanatham, Van Vo

Keywords(s):

Category(s): All, Technology Classifications > Chemistry

Synthetic Procedure and Cancer Treatment Using Cisplatin Derivatives

Invention SummaryA series of cisplatin derivatives were synthesized and characterized, superseding cisplatin, carboplatin, and oxaliplatin—compounds used for the clinical treatment of various cancers. The synthetic process for the manufacture of these compounds and their analogues are provided. The antitumor activities of these compounds were...

Published: 6/4/2015 | Inventor(s): Pradip Bhowmik, Haesook Han, Bryan Spangelo, Pear (ontida) Tanthmanatham, Van Vo

Keywords(s):

Category(s): Chemistry, All