Search Results - jose+rodriguez

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Methods for Determining Drug-Target Structures by Combining Mass Spectrometry and Electron Diffraction (UCLA Case No. 2025-229)
UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel approach to study protein-ligand interactions by integrating native mass spectrometry with electron diffraction. BACKGROUND: The accurate characterization of small molecule-protein interactions is crucial for biomedical research. High-throughput structural methods,...
Published: 10/29/2025   |   Inventor(s): Jose Rodriguez
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Mass Spectrometry, Chemical > Synthesis, Chemical > Chemical Sensors, Chemical > Chemical Processing & Manufacturing, Chemical > Instrumentation & Analysis, Diagnostic Markers > Targets And Assays, Electrical > Sensors, Electrical > Instrumentation, Life Science Research Tools > Research Methods, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Screening Libraries, Life Science Research Tools > Lab Equipment, Mechanical > Sensors, Mechanical > Instrumentation, Optics & Photonics > Microscopy, Optics & Photonics > Spectroscopy
2020-409 METHODS FOR THE DETERMINATION OF ATOMIC AND MOLECULAR STRUCTURES FROM DIGITALLY DEFINED REGIONS OF INTEREST
UCLA researchers from the Department of Chemistry and Biochemistry have developed a novel method to obtain atomic and molecular structures from digitally defined regions of a sample. BACKGROUND:Crystallography and diffraction experiments allow insightful looks into the atomic structure of materials. The usefulness of crystallography is vast, ranging...
Published: 7/17/2025   |   Inventor(s): Jose Rodriguez, Marcus Gallagher-Jones, Andrew Minor
Keywords(s): Imaging, Life Science Research Tools, Structures
Category(s): Life Science Research Tools > Research Methods, Life Science Research Tools > Microscopy And Imaging
The Cryoem Method Microed as a Powerful Tool for Small Molecule Structure Determination (UCLA Case No. 2019-360)
SUMMARYUCLA researchers in the Department of Chemistry and Biochemistry have developed a novel use of the cryogenic electron microscopy (CryoEM) method electron micro-diffraction (MicroED) to provide routine and unambiguous structural determination of small organic molecules.BACKGROUNDNuclear magnetic resonance (NMR) spectroscopy has been a mainstay...
Published: 7/17/2025   |   Inventor(s): Hosea Nelson, Jose Rodriguez, Brian Stoltz
Keywords(s): Life Science Research Tools, Research Methods, Targets And Assays
Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods, Diagnostic Markers > Targets And Assays