Search Results - jordan+shavit

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Inhibition of a Cholesterol Metabolism Gene for Effectively Treating Sepsis
Pharmacologically Blocking Specific Cholesterol Gene to Treat and Reduce Early Death from Sepsis This cholesterol metabolism gene is upregulated in sepsis patients with poor prognoses, and its inhibition shows promise as an effective treatment. Sepsis is the body’s extreme immune response to an existing infection, giving rise to an enhanced chain...
Published: 1/22/2024   |   Inventor(s): Faheem Guirgis, Vinitha Jacob, Jordan Shavit, Srinivasa Reddy
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Human Health Care > Others
Use of Retinoids in Congenital Erythropoietic Porphyria
Invention Summary: Congenital erythropoietic porphyria (CEP) is an unaddressed orphan disease caused by a rare genetic disorder leading to accumulation of uro/coproporphyrin-I (uro-I) in tissues due to inhibition of the enzyme uroporphyrinogen-III synthase. Clinical manifestations of CEP include bone fragility, severe photosensitivity, and photo-mutilation....
Published: 8/28/2024   |   Inventor(s): Bishr Omary, Jordan Shavit
Keywords(s): Small molecules
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Healthcare & Life Sciences