Search Results - jonathan+nelson

1 Results Sort By:
Split-luciferase complementation to measure soluble epoxide hydrolase dimerization
Technology Overview Soluble epoxide hydrolase (sEH) inhibition is a therapeutic target for a large number of cardiovascular diseases. Disrupting dimerization of sEH reduces hydrolase activity and shifts the sub-cellular localization of sEH to peroxisomes. The current technology is a split-firefly luciferase assay that not only measures disruption of...
Published: 9/19/2023   |   Inventor(s): Jonathan Nelson, Nabil Alkayed, Xiangshu Xiao
Keywords(s): Biological Materials, Research Tools - Screening
Category(s): Biological Materials, Research Tools