Search Results - john+robbins

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Moraxella Catarrhalis Lipooligosaccharide Based Conjugate Vaccines for the Prevention of Otitis Media and Respiratory Infections
Moraxella catarrhalis is one of the three leading causative agents of otitis media in children. This is due in part to the current immunizations of children with Streptococcus pneumoniae polysaccharide and conjugate vaccines to prevent otitis media. The proportion of otitis media caused by pneumococcal strains covered by the vaccines have decreased...
Published: 10/28/2024   |   Inventor(s): John Robbins, Xin-xing Gu
Keywords(s): BBXXXX, BCXXXX, BRANHAMELLA, CATARHALIS, Catarrhalis, DC4XXX, DCXXXX, DETOXIFIED, DXXXXX, HAEMOPHILUS, Haemophilus influenzae, Humans, Immunization, INFECTIONS, INFLUENZAE, Intranasal, Lipooligosaccharide, LIPOOLIGOSACCHARIDE-BASED, MORAXELLA, NONTYPEABLE, OTITIS MEDIA, Patent Category - Biotechnology, Prevention, Tetanus, UAXXXX, Vaccine, With...
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Vaccines, TherapeuticArea > Rare / Neglected Diseases
Recombinant Modified Bacillus anthracis Protective Antigen for Use in Vaccines
This invention relates to improved methods of preparing Bacillus anthracis protective antigen (PA) for use in vaccines. PA is a secreted, non-toxic protein with a molecular weight of 83 KDa. PA is a major component of the currently licensed human vaccine (Anthrax Vaccine Adsorbed, AVA). Although the licensed human vaccine has been shown to be effective...
Published: 10/28/2024   |   Inventor(s): John Robbins, Stephen Leppla, Rachel Schneerson, M Rosovitz
Keywords(s): Anthrax, ANTIGEN, Chromosome 18 ring, Chymotrypsin-Sensitive, CREATION, Cutaneous anthrax, DAXXXX, DBXXXX, DC4XXX, DC6XXX, DCXXXX, DDXXXX, DELETIONS, DXXXXX, Furin-Cleavage..., Loop, MOLECULE, Protective, R 18, recombinant, rPA, STABLE, UAXXXX
Category(s): Application > Diagnostics, TherapeuticArea > Rare / Neglected Diseases, Application > Research Materials, TherapeuticArea > Infectious Disease, Application > Therapeutics, Application > Vaccines