Search Results - john+o%27bryan

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Monobody R15 targets the nucleotide free state of RAS to block oncogenic signaling and transformation
Technology: Researchers at MUSC and NYU Langone Medical Center have identified a synthetic protein (R15) that selectively binds to the nucleotide-free state of the RAS proto-oncogene (apoRAS) and is the first experimental tool to selectively inhibit the signaling and oncogenic activity of selected oncogenic RAS mutants (Figure 1). The synthetic protein...
Published: 4/29/2024   |   Inventor(s): John O'Bryan, Shohei Koide, Akiko Koide
Keywords(s):  
Category(s): BioPharma
Non invasive embryo screening for improved human IVF outcomes
Market NeedDespite growth in industry demand, IVF cycles currently result in low success rates, with reports indicating less than 20% of cycles result in a live birth. While part of this is attributable to the physical environment of the individual patients, part of the high fail rate of IVF is attributable to the clinical elements of the IVF process,...
Published: 9/21/2018   |   Inventor(s): Jeremy Thompson, Hannah Brown, Martin Gosnell, John Ryan
Keywords(s):  
Category(s): Bioinformatics, Biology, Computer Software, Diagnostic, Imaging