Search Results - john+frost

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Biosynthetic Route to Phloroglucinol Synthesis
Executive Summary: Phloroglucinol (1,3,5 trihydroxybenzene) is used in the production of a plethora of applications such as explosive or propellant compounds, medicaments, cosmetics, dyes, and others which make it such a sought-after resource. However, Phloroglucinol is difficult to synthesize by chemical synthesis and alternative routes are desired....
Published: 8/10/2023   |   Inventor(s): John Frost
Keywords(s):  
Category(s): Chemicals, Pharmaceutical
Pyruvate-Based Pathway for Synthesis of 3-dehydroshikimate
Figure 1: (a) carbohydrate phosphotransferase; (b) KDPGal aldose, D-erythrose 4-phosphate; (c) DAHP synthase, D-erythrose 4-phosphate; (d) shikimate pathway enzymes. Executive Summary: 3-dehydroshikimate, a highly versatile compound that is currently limitedly produced, is used in supporting the creation of novel treatments of influenza...
Published: 8/10/2023   |   Inventor(s): John Frost
Keywords(s):  
Category(s): Chemicals, Pharmaceutical
Boron Based Catalysts for Cycloaddition Reactions
Executive Summary Increasing there is greater interest in replacing petroleum based chemicals with bio-based alternatives. The packaging market in particular, has actively sought “greener” alternatives for important materials such as poly(ethylene terephthalate), a.k.a. PET. MSU researchers have developed a new catalyst and method to make...
Published: 8/1/2023   |   Inventor(s): John Frost, Peng Zhang
Keywords(s):  
Category(s): Chemicals, Packaging
Synthesis of Caprolactam from Lysine
Executive Summary Caprolactam is used in important polymer products such as the polyamide Nylon 6. Most Caprolactam is produced from petroleum based feedstocks and there is a desire for a more sustainable route for making the monomer. MSU researchers have developed a technology for synthesizing epsilon-caprolactam from L-lysine with yields up to 75%...
Published: 5/25/2023   |   Inventor(s): John Frost
Keywords(s):  
Category(s): Chemicals, Environmental
Methods and Reagents for Site-Specific Labeling of Peptides and Proteins
Brief Description: Methods for site-specific protein functionalization find a broad range of applications in the context of protein detection, imaging, and purification, in the development of improved protein-based therapeutics (e.g. via PEGylation), and in the preparation of protein microarrays. This invention describes a new chemical method...
Published: 5/7/2024   |   Inventor(s): Rudi Fasan, John Frost
Keywords(s):  
Category(s): Research Tools