Inteum Company
Links
seedsprint
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - james+kelley
1
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Peptide Mimetic Ligands of Polo-like Kinase 1 Polo Box Domain
Abstract: Polo-like kinase 1 (Plk1) is a critical protein involved in regulation of mitosis, and aberrant expression of this kinase is found in various cancer types. Inhibition of Plk1 is currently being pursued in pre-clinical drug development for novel anti-cancer therapeutics. Plk1 contains an allosteric domain, known as the polo-box domain (PBD),...
Published: 5/22/2024
|
Inventor(s):
Terrence Burke
,
Wen-Jian Qian
,
Kyung Lee
,
Jung-Eun Park
,
James Kelley
Keywords(s):
Burke
,
CANCER
,
mitosis
,
Peptide Inhibitor
,
polo-box domain (PBD)
,
Polo-like kinase 1 (Plk1)
,
therapeutic
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Oncology
,
Application > Therapeutics