Search Results - hek293

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Cell Lines Expressing Nuclear and/or Mitochondrial RNAse H1
Abstract: The National Institute of Child Health & Human Development (NICHD), Program in Genomics of Differentiation, seeks interested parties to further co-develop small molecule inhibitors of RNase H1, especially in regards to genome instability, transcription, and translation. RNase H1 has been shown to remove RNA/DNA hybrids and either too much...
Published: 4/8/2024   |   Inventor(s): Robert Crouch, Yutaka Suzuki
Keywords(s): DNA/RNA hybrid, HEK293, mtDNA, RNAse H1
Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Immunology, TherapeuticArea > Oncology
Improved Large Scale Production of Adeno-Associated Viruses
Enables a More Efficient and More Potent Production of AAV VectorsThis production of highly concentrated and potent Adeno-Associated Virus (AAV) vectors has significant advantage over available protocol and allows for large-scale manufacturing of the virus. More than 6 percent of all gene therapy clinical trials worldwide use AAV vectors due to their...
Published: 6/27/2021   |   Inventor(s): Barry Byrne, Nathalie Clement, Laura Adamson
Keywords(s): AAV, Gene Therapy, HEK293, HSV
Category(s): Technology Classifications > Human Health Care > Gene Therapy