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Search Results - hai+yao
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Endothelium-Specific Laminin Reporter Mouse Line Laminin-mCherry/eGFP+/–; Cdh5-CreER+/– Mouse Line
Advantages Enables endothelial-specific labeling of laminin-γ1 in vivo. Tamoxifen-inducible system allows temporal control of recombination. Dual-color fluorescence distinguishes target cell-derived laminin from other cell-derived laminin. Co-localization with laminin-γ1 antibody confirms biological fidelity. Facilitates mapping...
Published: 11/25/2025
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Inventor(s):
Yao Yao
Keywords(s):
Animal Models
,
Research Tools
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
Novel Laminin Reporter Mouse Line for in vivo Imaging and Laminin Biology Research (Laminin-mCherry/eGFP+/-) Pre-Cre
Advantages First-ever dual-color laminin reporter mouse line. Enables visualization of laminin-γ1 expression in vivo with high fidelity. mCherry signal replicates endogenous laminin distribution without Cre activation. No background eGFP signal ensures clean baseline imaging. Targets the widely expressed γ1 subunit, enhancing...
Published: 10/9/2025
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Inventor(s):
Yao Yao
Keywords(s):
Animal Models
,
Neuroscience
,
Research Tools
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
Method, System and Application for 3D Molecular Diffusion Tensor Measurement and Structural Imaging
Fluorescence recovery after photobleaching (FRAP) is a versatile and widely used technique for measuring molecular diffusion properties within solutions, cells, tissues, biomaterials and the food and pharmaceutical industries. While it is a standard tool in biomedical and environmental research, all existing FRAP systems can only measure 2D diffusion,...
Published: 10/8/2024
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Inventor(s):
Hai Yao
,
Tong Ye
,
Peng Chen
,
Xun Chen
Keywords(s):
Category(s):
Biotechnology
Rib Fixation Device for Treatment of Early Onset Scoliosis and Spinal Deformities
This rib fixation device attaches expanded titanium hooks on two or four ribs, improving stability of fixation for safer management of upper thoracic instabilities. With early onset scoliosis (EOS) having an incidence of approximately 1-2 per 1000 births, and with frequent complications of originally untreated individuals, care for severe thoracic deformations...
Published: 10/8/2024
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Inventor(s):
Gregory Wright
,
Hai Yao
,
Richard Gross
Keywords(s):
Category(s):
Biomedical Sciences
Rib Hook Fixation Device
Technology: Inventors have developed a rib hook fixation device to control severe kyphosis (greater than 40° sagittal curve). The rib device is a combination of newly designed rib hooks that provide stress reduction with improved curvature and profile to better fit rib anatomy, and can be sized for children or adults. Pedicle screws are...
Published: 12/4/2025
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Inventor(s):
Gregory Wright
,
Hai Yao
,
Richard Gross
Keywords(s):
Category(s):
MedTech