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Search Results - gsd-1a
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Improved Gene Therapy Vectors for the Treatment of Glycogen Storage Disease Type Ia (
GSD-1a
)
Abstract: GSD-Ia is an inherited disorder of metabolism associated with life-threatening hypoglycemia, hepatic malignancy, and renal failure caused by the deficiency of glucose-6-phosphatase-alpha (G6Pase-alpha or G6PC). Current therapy, which primarily consists of dietary modification, fails to prevent long-term complications in many patients, including...
Published: 4/8/2024
|
Inventor(s):
Janice Chou
,
Barry Byrne
Keywords(s):
Chou
,
GSD-1a
,
hepatic malignancy
,
hyperlipidemia
,
hypoglycemia
,
National Institute of Child Health and Human Development
,
NICHD
Category(s):
TherapeuticArea > Nephrology
,
Application > Therapeutics
,
Collaboration Sought > Licensing
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Endocrinology