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Anti-Thrombin Nanoparticles and Therapeutics to Treat Necrotizing Enterocolitis
Advantages: Bivalirudin-tagged nanoparticles bind and neutralize nascent thrombin in clots, minimizing systemic anticoagulant effects Anti-thrombin nanoparticle confines its anticoagulant activity to sites of clot formation, limiting excessive systemic coagulation inhibition Dual therapeutic and diagnostic potential allows clinicians to treat NEC...
Published: 2/5/2025   |   Inventor(s): Akhil Maheshwari, Samuel Wickline, Koppenruncholan Namachivayam, Hua Pan
Keywords(s): Gastrointestinal / Digestive Health, Pharmaceuticals
Category(s): Technology Classifications > Medical > Pharmaceuticals