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Murine Models of an Autoinflammatory Disease, Familial Mediterranean Fever (FMF), to Study the Pathophysiology of Inherited Disorders of Inflammation and Evaluate New Therapies
This technology includes mouse models (heterozygous for the knock-in (KI) and homozygous for the knock-out (KO)) to be used as research reagents and to study molecular mechanisms and potential therapies for Familial Mediterranean fever (FMF). FMF is the prototype of a group of inherited disorders characterized by recurring, spontaneous episodes of fever...
Published: 10/28/2024   |   Inventor(s): Jae Chae, Daniel ("Dan") Kastner
Keywords(s): Autoinfla~-~atory, Autoinflamatory, Disease, FAMILIAL, FEVER, FMF, MEDITERRANEAN, Models, Murine, VPXXXX, WIXXXX, XEXXXX
Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Dental, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease