Search Results - florence+wagner

1 Results Sort By:
Novel treatment for CTNNB1 syndrome
SUMMARY Tufts University investigator, Michelle Jacob, and Broad Institute’s Florence Wagner, have shown significant improvements in symptoms of CTNNB1 neurodevelopmental disorder in a heterozygous mouse model using a novel small molecule targeting β-catenin signaling. BACKGROUND The CTNNB1 mutation is an extremely rare genetic neurodevelopmental...
Published: 4/29/2024   |   Inventor(s): Michele Jacob, Jonathan Alexander, Florence Wagner
Keywords(s):  
Category(s): Therapeutic, Therapeutic: small molecule