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Formulation of a Modified Stable FGF-1 (TTHX1114) to Accelerate Corneal Endothelium Regeneration
This technology includes the use of a novel formulation for an engineered version of Fibroblast Growth Factor 1 (FGF1), TTHX1114, that can be used to accelerate regeneration of the corneal endothelium after surgical lesions. FGFs are well-established regulators of migration and proliferation of corneal endothelial cells (CECs).
Published: 10/28/2024   |   Inventor(s): Vinay Vyas, Hui Fang Dong, Asaf Alimardanov, Gautam ("George") Mitra, Trevor Broadt, David Eveleth
Keywords(s): FGF-1, FORMULATION, Modified, PRESERVATION, STABLE, TTHX1114, VPXXXX, WIXXXX, WKXXXX, XEXXXX
Category(s): TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, TherapeuticArea > Ophthalmology, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, Application > Research Materials, TherapeuticArea > Cardiology