Search Results - donor

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Alloreactive T Cell Depletion Method For Preventing Graft-Versus-Host Disease
The invention relates to the use of adenosine to deplete alloreactive T cells from donor grafts to prevent graft-versus-host disease (GVHD). The method includes culturing donor cells that include T cells with recipient antigen presenting cells (APCs) to form a mixture of cells. The recipient’s APCs activate donor T cells. The activated T cells are...
Published: 10/28/2024   |   Inventor(s): Gregory Whitehill, John Barrett, Dhanalakshmi (Donna) Chinnasamy
Keywords(s): Alloreactive, Cell, DEPLETION, Disease, DONOR, GRAFTS, GRAFT-VERSUS-HOST, GVHD, Listed LPM Maddox as of 4/15/2015, LYMPHOCYTE, lymphocytes, Method, Novel, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Prevent, SELECTIVE, Stem, T, YAXXXX
Category(s): Collaboration Sought > Licensing
Image Guided Systems and Methods for Organ Viability Assessment
The number of patients for organ transplants continues to grow, without an increase in the number of organs available for transplant. This has increased interest in transplanting organs from non-traditional sources, such as donations after cardiac death. However, there are currently no methods to objectively measure the effects of resuscitation and...
Published: 10/28/2024   |   Inventor(s): Allan Kirk, Eric Elster, Frederick Gage, Alexander Gorbach
Keywords(s): AA1XXX, AA3BXX, AA3XXX, AAXXXX, ASSESSMENT, AXXXXX, DEVICE, DONOR, During, Guided, Image, Method, ORGANS, ORS to NIBIB, Resuscitation, VIABILITY
Category(s): Collaboration Sought > Licensing