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Search Results - dna+repair+therapeutics
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Inhibition of Gli1 Increases Sensitivity to Cisplatin
OPPORTUNITY Platinum-based anticancer agents are among the most widely used agents in clinical oncology. Nucleotide excision repair (NER) is the pathway through which platinum–DNA damage is repaired and, ERCC1 is a useful biomarker for the NER process in human cells. Understanding the molecular and pharmacological control of NER may allow for...
Published: 1/9/2018
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Inventor(s):
Eddie Reed
,
Rajeev Samant
Keywords(s):
Category(s):
Cancer Therapeutics
,
DNA Repair Therapeutics
,
All Technologies