Search Results - diseases%3a+infectious

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Intrinsically cell-penetrant, autophagy-inducing peptides
Tufts University investigator, Joshua Kritzer, has developed a family of modified peptides that induce the biological process of autophagy. These peptides are potential therapeutics for diseases in which deregulation or dysfunction of autophagy plays a role. ProblemThere is a growing need to address autophagy in neurodegenerative disorders, muscular...
Published: 6/8/2020   |   Inventor(s): Joshua Kritzer, Leila Peraro, Beth Levine
Keywords(s):  
Category(s): Diseases: infectious
Inhibitors of Clostridium difficile spore germination and outgrowth
Inhibitors of Clostridium difficile spore germinationTufts case T001523Technology• Spore formation by Clostridium difficile is a significant obstacle to overcoming hospital-acquired C. difficile-associated disease (CDAD). Spores are resistant to heat, radiation, chemicals, and antibiotics, making a contaminated environment difficult to clean....
Published: 3/19/2021   |   Inventor(s): Abraham Sonenshein, Joseph Sorg
Keywords(s):  
Category(s): Diseases: infectious, Screening: target, Therapeutic: antibiotic, Therapeutic: small molecule