Search Results - joshua+kritzer

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A Kit to Quantify Cell Penetration
DESCRIPTIONTufts investigator, Joshua Kritzer, has developed a novel high throughput assay, Chloroalkane Penetration Assay (CAPA), to quantitatively measure the compartment-specific cell penetration of any externally applied agent. CAPA uses a cell line expressing a HaloTag fusion protein that is exclusively localized to the cytosol, nucleus, or other...
Published: 6/8/2020   |   Inventor(s): Joshua Kritzer
Keywords(s):  
Category(s): Chemistry
Intrinsically cell-penetrant, autophagy-inducing peptides
Tufts University investigator, Joshua Kritzer, has developed a family of modified peptides that induce the biological process of autophagy. These peptides are potential therapeutics for diseases in which deregulation or dysfunction of autophagy plays a role. ProblemThere is a growing need to address autophagy in neurodegenerative disorders, muscular...
Published: 6/8/2020   |   Inventor(s): Joshua Kritzer, Leila Peraro, Beth Levine
Keywords(s):  
Category(s): Diseases: infectious