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Search Results - dhulfiqar+abed
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Novel Inhibitors of Keap1-Nrf2 Protein-Protein Interaction
Novel Small Molecule Direct Inhibitors of Keap1-Nrf2 Protein-Protein Interaction Invention Summary: Nrf2 is a key transcription factor mediating anti-inflammatory and antioxidant responses in the body. Keap1 is a well-known repressor of Nrf2 that targets Nrf2 for its rapid proteasomal degradation. Dysfunctional Keap1-Nrf2 axis contributes to...
Published: 5/15/2024
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Inventor(s):
Longqin Hu
,
Dhulfiqar Abed
Keywords(s):
Small molecules
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Therapeutics