Search Results - david+wood

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Treatment of primary hyperoxalurias with small molecule lactate dehydrogenase inhibitors such as WO2018005807A1

This technology includes the use of novel lactate dehydrogenase (LDH) inhibitors, including WO2018005807A1, for the treatment of primary hyperoxalurias (PHs). PHs are rare autosomal recessive disorders caused by overproduction of oxalate, leading to recurrent calcium oxalate kidney stone disease, and in some cases end-stage renal disease. One potential...

Published: 10/28/2024 | Inventor(s): Daniel Urban, Leonard Neckers, Ross Holmes, David Wood, Matthew Hall

Keywords(s): DEHYDROGENASE, Hyperoxalurias, Inhibitors, LACTATE, MOLECULE, Primary, Small, TREATING, VPXXXX, WIXXXX, WKXXXX, XEXXXX

Category(s): TherapeuticArea > Cardiology, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Research Materials

Treating Short Gut Syndrome and Preventing Necrotizing Enterocolitis Using Synthesized FA-EGF

Published: 3/1/2022 | Inventor(s): Marvin Meyers, Stacy Arnett, Peter Ruminski, David Wood, Matthew Yates

Keywords(s):

Category(s): Therapeutics

Simple, Economical Bioseparation Technique Using Self-Cleaving Thermally Responsive Fusion Tags

Princeton Invention # 05-2188 Researchers in the Chemical Engineering Department at Princeton University have developed a new economical method for the purification of recombinant proteins expressed in E. coli and other expression host cells. This method relies on a self-cleaving elastin-like polypeptide (ELP) fusion...

Published: 7/3/2023 | Inventor(s): David Wood, Mahmoud Banki

Keywords(s):

Category(s): Biotechnology/Pharmaceuticals

Engineered In Vivo Biosensors for Nuclear Hormone Receptor Ligands

Princeton University Invention # 04-2095 Researchers in the Chemical Engineering Department at Princeton University have developed a new type of biosensor using Escherichia coli that can report ligand binding to eukaryotic nuclear hormone receptors. This system has been optimized to report the presence of endocrine-active compounds through...

Published: 2/14/2024 | Inventor(s): David Wood, Georgios Skretas

Keywords(s):

Category(s): Biotechnology/Pharmaceuticals

New Simple, Economical Bioseparation Technique Using Self-Purifying, Self-Cleaving Affinity Tags

Princeton Invention # 04-2076 Researchers at Princeton University have developed a new economical method for the purification of recombinant proteins expressed in E. coli. In this method, the host cells simultaneously produce both an affinity tagged product protein and an easily recovered granular affinity carrier. The...

Published: 8/21/2023 | Inventor(s): David Wood, Mahmoud Banki, Tillman Gerngross

Keywords(s):

Category(s): Biotechnology/Pharmaceuticals