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Search Results - daniel+herr
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Mitochondrial targeted HDAC inhibitors for the treatment of heart failure and related diseases and disorders (MitoDACs)
Technology: Researchers at MUSC have discovered HDAC1 is present in the adult cardiac myocyte mitochondria. A series of HDAC1 inhibitors that target mitochondria have been made (MitoDACs). One of the analogs, LL-66, localizes to the mitochondria and is absent from the nucleus in isolated adult rat cardiac myocytes. Inhibiting activity of HDAC1...
Published: 4/29/2024
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Inventor(s):
Donald Menick
,
Chung-Jen (James) Chou
,
Daniel Herr
,
Xiaoyang (李晓杨) Li
Keywords(s):
Category(s):
BioPharma