Search Results - clinical+trials

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Cancer Therapeutic with Increased Efficacy and Reduced Side Effects
Uses Small Drug-Like Molecules to Prevent Cancer Cell ProliferationThis breakthrough approach to treating cancer is efficacious and has limited side effects. Cancer is a leading cause of death in the United States, accounting for one in four deaths annually, according to the American Cancer Society. An estimated 595,600 Americans will die of cancer-related...
Published: 6/27/2021   |   Inventor(s): Peter Stacpoole, David Ostrov, Arun Srivastava
Keywords(s): breast cancer, Cancer Therapy, Clinical trials, Colon Cancer, PDK2, Structure-based Drug Design
Category(s): Technology Classifications > Human Health Care > Therapeutics
Advancement in Platinum Based Cancer Therapeutics
Project ID: D2014-33Novelty: Small drug like molecules that inhibits DNA repair factors for cisplatin (and other platinum based drugs) resistance towards solid tumors, thereby increasing cisplatin cytotoxicity and efficacy. Value proposition: One of the limitations of chemotherapy in ovarian cancer is the innate/acquired drug resistance in cancer cells....
Published: 6/18/2024   |   Inventor(s): Paul Erhardt, Stephan Patrick, Christopher Trabbic
Keywords(s): Cisplatin, Clinical Trials, DNA Repair, Ovarian Cancer, Platinum
Category(s): Oncology, Tools