Search Results - christopher+natale

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Selective Receptor Modulators for Skin Depigmentation
Small-molecule compositions modulate non-canonical sex steroid receptors to decrease, prevent, or reverse skin pigmentation gain in mammalian subjects. Problem: Skin hyperpigmentation can arise from pregnancy, hormones, inflammatory conditions, or skin injury. Existing approaches may not address receptor pathways that regulate melanocyte pigmentation....
Published: 4/6/2026   |   Updated: 4/6/2026   |   Inventor(s): Todd Ridky, Christopher Natale
Keywords(s): Dermatology, Small Molecule
Category(s): Technology Classifications > Therapeutics
Novel Uses of Androgen Receptor Inhibitors in Cancer
Repurposing of androgen receptors inhibitors for prostate cancer treatment to treat other cancer in males such as melanoma. Problem: For many cancer types, women have lower incidence and better outcomes than men. The role of sex steroid hormones, such as estrogen and testosterone, has been studied in reproductive organ cancers such as prostate and...
Published: 8/1/2025   |   Updated: 4/28/2020   |   Inventor(s): Todd Ridky, Cristina Aguirre Portolés, Christopher Natale
Keywords(s): Men's Health, Oncology
Category(s): Technology Classifications > Therapeutics