Search Results - charuka+wickramasinghe

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Methods For The Prediction Of Drug Penetration and Exposure In The Human Brain
Description: A novel 9‑compartment physiologically based pharmacokinetic model that predicts drug distribution and exposure in the human brain and brain tumors to improve treatment outcomes. SpatialCNS-PBPK is an advanced, web-based platform implementing a 9-compartment PBPK model that simulates spatial pharmacokinetics of drugs within the central...
Published: 11/6/2025   |   Inventor(s): Jing Li, Seongho Kim, Charuka Wickramasinghe
Keywords(s):  
Category(s): Technology Category > Life Science, Technology Category > Method, Technology Category > Drug Screening, Technology Category > Drug Delivery
2008-211 Peptide for Induction of Immune Tolerance as Treatment for Systemic Lupus Erythematosus (SLE)
Peptide for Induction of Immune Tolerance as Treatment for Systemic Lupus Erythematosus (SLE)SUMMARYUCLA investigators have invented the D form of an artificial synthetic peptide to induce suppressive T cells that prevent anti-DNA production in mice. The L form of the peptide is administered by injection; however, the new D form of the peptide is designed...
Published: 7/17/2025   |   Inventor(s): Bevra Hahn, Antonio La Cava, Fanny Ebling, Ram Singh, Ram Singh
Keywords(s):  
Category(s): Therapeutics, Therapeutics > Autoimmune
2008-211 Peptide for Induction of Immune Tolerance as Treatment for Systemic Lupus Erythematosus (SLE)
Peptide for Induction of Immune Tolerance as Treatment for Systemic Lupus Erythematosus (SLE)SUMMARYUCLA investigators have invented the D form of an artificial synthetic peptide to induce suppressive T cells that prevent anti-DNA production in mice. The L form of the peptide is administered by injection; however, the new D form of the peptide is designed...
Published: 7/17/2025   |   Inventor(s): Bevra Hahn, Antonio La Cava, Fanny Ebling, Ram Singh, Ram Singh
Keywords(s):  
Category(s): Therapeutics, Therapeutics > Autoimmune