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Intranasal leptin to treat opioid-induced respiratory depression (OIRD) in obese patients
­Respiratory depression is the leading cause of morbidity and mortality associated with opioids. Patients with obesity experience pain and need opioids more frequently than normal-weight individuals. Chronic consumption of opioids is associated with addiction, physical dependence, and tolerance. Tolerance leads to requirement of higher doses of...
Published: 9/11/2024   |   Inventor(s): David Mendelowitz, Vsevolod Polotsky, Carla Freire
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Category(s): Technology Classifications > Therapeutics