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Search Results - carissa+grose
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Improved Production of Prenylated Protein in Insect Cells
Abstract: KRAS and other Ras-family enzymes are an important component of over 30% of human cancers, however, no effective therapeutics targeting Ras or Ras-driven cancers are currently available. The production of Ras proteins in vitro is required for the identification and characterization of Ras targeting drugs. An important step in producing the...
Published: 5/22/2024
|
Inventor(s):
Dominic Esposito
,
Carissa Grose
,
William Gillette
Keywords(s):
CANCER
,
KRAS
,
RAS
,
RESEARCH MATERIAL
Category(s):
Application > Research Materials
,
TherapeuticArea > Oncology
,
Collaboration Sought > Licensing
Bac-2-the-Future: An Improved System for Production of Recombinant Baculovirus
Abstract: Baculoviruses have been used for decades to produce proteins in insect cell hosts. Current systems for generating recombinant baculovirus have several shortcomings which prevent their easy use in high-throughput applications. Researchers within the Frederick National Laboratory for Cancer Research have developed an improved system called...
Published: 5/22/2024
|
Inventor(s):
Dominic Esposito
,
Carissa Grose
Keywords(s):
B2F
,
Bac-2-the-Future
,
Baculovirus
,
Esposito
,
Insect Cells
,
Protein Production
Category(s):
TherapeuticArea > Gastroenterology
,
TherapeuticArea > Endocrinology
,
TherapeuticArea > Infectious Disease
,
TherapeuticArea > Cardiology
,
TherapeuticArea > Opthamology
,
TherapeuticArea > Eye / Ear / Nose / Throat
,
TherapeuticArea > Reproductive Health
,
TherapeuticArea > Immunology
,
TherapeuticArea > Dermatology
,
Collaboration Sought > Licensing
,
Application > Research Materials
,
TherapeuticArea > Oncology
,
TherapeuticArea > Nephrology