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Search Results - brian+callahan
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Enzymatic Bioluminescent Beacons for Ultra-Sensitive, Rapid Nucleic Acid Detection
This invention introduces enzymatic bioluminescent beacons that generate bright, low-background light only upon binding their target sequence. A site-specific ligation strategy forms uniform 1 to 1 nanoluciferase–hairpin conjugates, enabling rapid, picomolar sensitivity detection with precise single-base discrimination in streamlined, equipment-light...
Published: 11/14/2025
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Inventor(s):
Brian Callahan
Keywords(s):
Technologies
Category(s):
Campus > Binghamton University
Traceless Protein–DNA Conjugation for Next-Gen Biotech
This invention introduces a fast, site-specific enzymatic method for attaching oligonucleotides to proteins with near-traceless precision, enabling cleaner, more functional conjugates for diagnostics, therapeutics, and nanotechnology. Background: Conventional methods for protein–oligonucleotide conjugation often suffer from slow reaction rates,...
Published: 11/12/2025
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Inventor(s):
Brian Callahan
,
Timothy Owen
Keywords(s):
#SUNYresearch
,
Technologies
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Research Tools and Reagents
,
Campus > Binghamton University