Search Results - bingyu+xin

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Accelerated Image Reconstruction (MRI)
Comparison of the adaptive unrolled method's effectiveness against two other contemporary deep unrolling techniques (M1 and M2). M1 produces a blurry reconstruction, M2 results in a clear but structurally inaccurate output. In contrast, the adaptive unrolling method achieves reconstruction that closely matches the Ground Truth in both sharpness...
Published: 12/17/2024   |   Inventor(s): Bingyu Xin, Dimitris Metaxas
Keywords(s):  
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Medical Imaging, Technology Classifications > Software & Algorithms, Technology Classifications > Software & Copyright, Technology Classifications > Artificial Intelligence & Machine Learning
Novel Zinc Metallochaperone (ZMC) Complexes for Treatment of p53-Mutated Cancers
A) Novel mechanism of action: a short exposure to ZMCs increases zinc levels in tumors enough to restore normal structure/function to mutant p53 which leads to p53 mediated cancer cell death. B) Novel formulation: Synthesizing ZMCs as a zinc-loaded complex (Zn-1) improves survival in a pancreatic cancer mouse model compared to the ZMC compound alone....
Published: 12/4/2024   |   Inventor(s): Darren Carpizo, David Augeri, Spencer Kimball, Xin Yu
Keywords(s): Anti-cancer, Small molecules
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics