Search Results - benjamin+umlauf

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Future drug-delivery system to treat brain tumors
Background/problem Glioblastoma (GBM) is the most common malignant, primary brain tumor observed in adults, occurring at an incidence rate of 3.19 per 100,000 persons in the United States in 2017. Even with complete surgical resection of the tumor and adjuvant chemotherapy, these tumors often reoccur, resulting in a median survival of ~15 months. Part...
Published: 6/6/2024   |   Inventor(s): Benjamin Umlauf, Bryan Davies, Austin Shipley, Gabriel Frampton
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery
Unlocking the brain: boosting CNS accumulation of glioblastoma drugs
Problem In the pursuit of optimizing the delivery of brain-penetrating drugs, researchers have explored innovative technologies to enhance their accumulation within the central nervous system (CNS). Traditional strategies such as altering drug chemistry or formulation have shown limited success in extending patient survival, particularly in the context...
Published: 2/13/2024   |   Inventor(s): Benjamin Umlauf
Keywords(s):  
Category(s): Life sciences > Therapeutics > Formulation, Life sciences > Therapeutics > Drug delivery