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Search Results - bcl2l1
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Bcl-x LoxP (
Bcl2l1
tm1.1Mam) Mouse Model for Developmental Biology Studies
Floxed Bcl-x: Conditional knockout of pro-survival Bcl-x in primordial germ cells was used to study the balance between pro-apoptotic Bax during embryogenesis. Bcl-x is a pro-survival protein that opposes the pro-apoptotic action of Bax which interacts with mitochondria to activate the caspase 9 pathway. Mice in which the Bcl-x gene is inactivated...
Published: 4/8/2024
|
Inventor(s):
Lothar Hennighausen
Keywords(s):
Bcl
,
Bcl2l1
,
IDXXXX
,
IXXXXX
,
LOXP
,
Mouse
,
R1XXXX
,
RXXXXX
,
Tm1/Mam
Category(s):
Collaboration Sought > Licensing
,
Application > Research Materials
,
Application > Diagnostics
,
Application > Therapeutics