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Therapeutic Peptide Treatment for Dyslipidemic and Vascular Disorders
This invention is directed to use of certain peptide analogs comprising multiple amphipathic helical domains that are able to promote cellular lipid efflux and stimulate lipoprotein lipase activity. As a result, administration of invention peptides lead to reduced incidences of hypertriglyceridemia without inducing toxicity. Existing peptides that stimulate...
Published: 10/28/2024   |   Inventor(s): Marcelo Amar, Alan Remaley
Keywords(s): 3-@hydroxyacyl-coa dehydrogenase deficiency, ApoA-I, HAD deficiency, HIS deficiency, Histidinemia, Hypertriglyceridemia, IB1XXX, IBXXXX, IXXXXX, Mimetic, Patent Category - Biotechnology, Peptides, VDXXXX, VHXXXX, WBXXXX, WJXXXX, YAXXXX, YBXXXX, YCXXXX
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, Application > Diagnostics, Application > Research Materials